PUBLICATIONS
| Title | The Effect of Carotid Endarterectomy on Cerebral Blood Flow and Cognitive Function. |
| Authors | Ghogawala Z, Amin-Hanjani S, Curran J, Ciarleglio M, Berenstein A, Stabile L, Westerveld M. |
| Presented | J Stroke Cerebrovasc Dis. 2012 May 1. [Epub ahead of print] |
| Summary | Non-invasive QMRA was used to assess the degree of flow impairment in carotid stenosis patients and to measure the flow improvement after carotid endarterectomy. |
| Conclusion | Patients with baseline flow impairment are more likely to show improvement in ICA and MCA blood flow after revascularization. Improvement in MCA blood flow was associated with improvement in the attention and executive functioning domains. |
| Title | Extracranial carotid plaque length and parent vessel diameter significantly affect baseline ipsilateral intracranial blood flow. |
| Authors | Douglas AF, Christopher S, Amankulor N, Din R, Poullis M, Amin-Hanjani S, Ghogawala Z. |
| Presented | Neurosurgery. 2011 Oct;69(4):767-73; discussion 773. |
| Summary | Quantitative MRA is used to estimate parent artery flow compromise in patients with unilateral carotid stenosis. |
| Conclusion | Both plaque length and vessel diameter were found to be independent predictors of carotid flow compromise, in addition to degree of stenosis. |
| Title | Endovascular intervention for delayed stenosis of extracranial-intracranial bypass saphenous vein grafts. |
| Authors | Qahwash O, Alaraj A, Aletich V, Charbel FT, Bulsara KR, Ho W, Valyi-Nagy T, Amin-Hanjani S. |
| Presented | J NeuroIntervent Surg (2012) doi:10.1136/neurintsurg-2011-010202. |
| Summary | QMRA is used to measure graft flow following EC-IC bypass. |
| Conclusion | Non-invasive quantitative phase contrast MR angiography was effective in predicting graft stenosis. |
| Title | In Vivo Evaluation of Quantitative MR Angiography in a Canine Carotid Artery Stenosis Model |
| Authors | Calderon-Arnulphi M, Amin-Hanjani A, Alaraj A, Zhao M, Du X, Ruland S, Zhou XJ, Thulborn KR, Charbel FT |
| Presented | Am J Neuroradiol 32:1552-59. September 2011 |
| Summary | The accuracy of non-invasive QMRA is evaluated by comparison with an invasive, gold standard ultrasonic transit time flowprobe. A vascular tourniquet was applied to the canine carotid artery to produce progressive stenosis and varying flow rates. |
| Conclusion | Non-invasive QMRA is accurate compared with the gold standard flowprobe in a canine arterial flow model with vessel stenosis. QMRA may be useful in evaluating the hemodynamic effects of stenosis in cerebrovascular atherosclerosis. |
| Title | Endovascular implantation of covered stents in the extracranial carotid and vertebral arteries: Case series and review of the literature |
| Authors | Alaraj A, Wallace A, Amin-Hanjani A, Charbel FT, Aletich V |
| Presented | Surgical Neurology International 2011, 2:67 |
| Summary | QMRA is used pre and post intervention to measure vessel flow |
| Conclusion | QMRA documents normalization of flow following endovascular placement of a covered stent graft in an extracranial cervical artery. |
| Title | Clinical utility of quantitative magnetic resonance angiography in the assessment of the underlying pathophysiology in a variety of cerebrovascular disorders |
| Authors | Brisman JL, Pile-Spellman J, Konstas AA |
| Presented | Eur J Radiol. 2011 Feb 10. [epub ahead of print] |
| Summary | The authors review 10 patients before and after their treatments for a range of cerebrovascular diseases. |
| Conclusion | This study supports incorporation of QMRA into mainstream cerebrovascular practice. The technique is unique in combining anatomic assessment, volumetric flow values and physiologic waveform information in the course of a single MR examination. |
| Title | Detection of Intracranial In-Stent Restenosis Using Quantitative Magnetic Resonance Angiography |
| Authors | Sepideh Amin-Hanjani, Ali Alaraj, Mateo Calderon-Arnulphi, Victor A. Aletich, Keith R. Thulborn, and Fady T. Charbel. |
| Presented | Stroke 2010;41:2534. |
| Summary | This study examines the value of serial vessel flow measurements using QMRA to detect in-stent restenosis (ISR). |
| Conclusion | In this preliminary series, a flow decrease on qMRA was highly predictive of angiographic in-stent restenosis. The degree of flow decrement also correlates with symptomatic ISR. |